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Description
In fact, oxidative stress can lead to the decrease of DNA-binding activities of activator protein-1 and CREB (cyclic AMP-response element-binding protein) which is associated with the reduction of BDNF (brain-derived neurotrophic factor) gene expression, as well as oxidative stress, and can result in impairment of NMDA channel function that is related to the decrease in BDNF gene expression
Recent studies have revealed that nuclear P53 also induces ferroptosis by suppressing the expression of SLC7A11, the gene encoding system x c , which, in a transcription-dependent manner, reduces cystine absorption and makes cells more susceptible to ferroptosis [76]
Circadian Misalignment Augments Markers of Insulin Resistance and Inflammation, Independently of Sleep Loss
10.1021/acs.jnatprod.9b00403
