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Safe Dosage Range 250-500mg daily (oral) shows significant melanin reduction with limited side effects

Sarma GN, Savvides SN, Becker K et al (2003) Glutathione reductase of the malarial parasite Plasmodium falciparum : crystal structure and inhibitor development

Autoimmune and Neuropathy: Chemotherapy-induced neuropathy: B12 supplementation may also be beneficial for patients with autoimmune conditions that cause nerve damage