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Description
HFE mutations in the elderly

discovered that downregulation of mTOR in LN patients leads to a reduction in STAT3 and Th17 cells within effector T cells, while inhibiting the AKT signaling pathway hinders the migration of Th17 cells towards inflammatory sites, effectively mitigating the chronic inflammatory process in LN (38, 156)

Nature 514 , 328334 (2014)

Microvascular and macrovascular complications of diabetes
