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Description
Once-per-week selinexor, bortezomib, and dexamethasone versus twice-per-week bortezomib and dexamethasone in patients with multiple myeloma (BOSTON): A randomised, open-label, phase 3 trial

900 to 1500 mcg three times daily (roughly 2.7 to 4.5 mg total) for 5 to 10 days following acute ischaemic event

R., Kapogiannis, D., & Martens, C

The question is: Does this compound need the local concentration spike, or is systemic exposure enough
