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Mechanisms of action Anti-CD38 antibodies exert their therapeutic effects via direct effector mechanisms on MM cells (i.e., CD38 enzymatic inhibition, direct induction of apoptosis) and through Fc-dependent immune mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), complement-directed cytotoxicity (CDC), and antibody-directed cellular phagocytosis (ADCP) (Fig

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CPT Codes Commonly Billed With M62.81 Common CPT families that pair with generalized weakness claims: E/M services for evaluation and medical decision making Physical therapy evaluation and re-evaluation codes Therapeutic exercise and neuromuscular re-education codes Gait training and functional performance testing codes Payer review focuses on one question: Do the documented deficits justify the billed services

Methylcobalamin is a naturally occurring form that may offer added benefits for those with severe deficiencies or neurological symptoms