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Thus, higher estrogen levels intrinsic to people with female gonads may lead to upregulated immune responses via estrogen-mediated expression of IFN
Notably, three distinct inhibitors of ferroptosis, including PUFAs, DFO, and Fer-1, effectively impede this process, thus creating new therapeutic possibilities for PD treatment

Our work uncovered a new mutagenic process and provides key mechanistic insights into cancer-associated mutational signatures

Erastin reduces cell viability, leading to oxidative stress, iron overload, and accumulation of lipid peroxides in human epidermal melanocytes
