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Jr., Hwang, J
Antiproliferative effect of ascorbic acid is associated with the inhibition of genes necessary to cell cycle progression
If the initial oxidative enzymes are overactive due to genetic variation, or if they are upregulated by a cytochrome inducer like chronic alcohol use or certain anticonvulsants, the production of toxic metabolites can overwhelm the conjugation capacity
Free Radic Biol Med 99: 8798
