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doi:10.3390/antiox12040834

This review highlights the role of IGF-1 in skeletal muscle, its importance during myogenesis, and its involvement in different disease conditions. Finally, IGF-1 LR3 helps inhibit muscle breakdown, thus preserving muscle protein content and mass as shown in a study using a rat model of hind limb suspension (HLS)

HolmstrmKMBairdLZhangYHargreavesIChalasaniALandJMet al

[DOI] [PubMed] [Google Scholar] 78.Cao R.Y., Li J., Dai Q., Li Q., Yang J
