glutathione and hydrogen sulfide Potential mechanisms of H2S-induced cytotoxicity. Hydrogen sulfide chemical biology: Pathophysiological

J Biol Chem 272:1851518517 Fu YL, Krasnovsky AA, Foote CS (1997) Quenching of singlet oxygen and sensitized delayed phthalocyanine fluorescence

Conversely, a few studies reported high levels of vitamin B12 in the blood of patients with a worse COVID-19 outcome 48,49 potentially due to cytolysis leading to the release of intracellular B12 into the plasma and disrupted B12 clearance by the liver, which is often affected in these patients 50

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Risk management Manufacturers need to establish a risk management plan to identify and assess potential risks in the production process, such as raw material contamination, equipment failure and human operational errors, etc