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Other signs may include shortness of breath, pale skin, stomach problems, such as constipation, diarrhea or gas, or nerve problems, like muscle weakness or tingling in fingers or toes. Over time, a deficiency of B12 can cause problems with balance, confusion, depression, poor memory and possibly dementia, and it can even cause permanent damage to the nervous system, Somers says

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Therefore, it is likely that the kinetics of reduction of plasma Hcy observed in current study are the direct result of expansion of intracellular folate pools by folate/B 12 supplementation

They can support your energy levels, but a balanced diet and regular exercise are key to losing weight effectively.