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Inhibition of IL-6 and TGF- production by ATRA was achieved by blocking the PKC-/NF-B and p38MAPK/NF-B pathways (38) and shifting the regulatory T/T helper 17 ratio and reducing the secretion of IL-17A (39)

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The first reported use of STS in calc was in 2004 (Cicone et al, AJKD 2004)

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