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Potential disease-modifying therapies for Huntingtons disease: lessons learned and future opportunities

The prodrug design of sofosbuvir enables its accumulation in the liver, thereby enhancing its efficacy in inhibiting HCV

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Alzheimers disease (Reduce attention deficiencies in some individuals after long-term treatment, especially when combined with acetylcholinesterase inhibitors ) Depression (Acetyl L-Carnitine supplement remarkably decrease depression symptoms) HIV infection (used for symptomatic management and nerve regeneration) Diabetic Neuropathy (Reduce pain, Enhance nerve conduction velocity, and nerve regeneration) Ischemia (acts as neuroprotective) Cognitive impairment due to alcohol abuse