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Heres why: Vitamins B1, B2, B3 (Thiamine, Riboflavin, Niacin) Needed for energy production Help the body process carbohydrates, fats and proteins Support the nervous system and mitochondrial function Niacinamide (a form of B3) is also used topically for acne due to its anti-inflammatory benefits Symptoms of deficiencies may include: Fatigue Cracked corners of the lips Inflammation of the tongue (glossitis) Skin problems like dermatitis Note: High doses of certain forms of niacin can trigger flushing, which may feel like its worsening skin conditions like rosacea

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VGLUT1 glutamatergic presynaptic marker Synapsin Fereira and Rapoport 2002 PSD-95 the postsynaptic marker to decipher neurotransmitter phenotypes

Lipid-based vehicles penetrate significantly better than water-based serums