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The limitations of this work are that we included RCTs, non-RCTs, and observational studies, which may lower the overall quality of evidence of the included studies
They might suggest a blood panel at the outset of treatment and then again after treatment has commenced for supplementation
However, it may cause mild discomfort for those with sensitive skin
(PubMed) Fernandez-Roig S, Lai SC, Murphy MM, Fernandez-Ballart J, Quadros EV
