glutathione reductase decreased nadph oxidase ncbi Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants NADPH Oxidase‐Like Nanozyme for High‐Efficiency

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Because of their high metabolic activity, the adrenal glands, which are required for the production of steroid hormones that regulate different physiological processes, are vulnerable to oxidative damage ( 4 Oxidative stresses Oxidative stress occurs when prooxidant molecules like ROS and reactive nitrogen species (RNS) get produced in excess when antioxidant systems are not working efficiently ( When ROS levels exceed the antioxidant defences of the body, they can damage lipids, proteins, and DNA

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Biochem Pharmacol 44: 19051915