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This process involves the binding of excess intracellular copper ions to lipoylated proteins in the tricarboxylic acid (TCA) cycle, leading to their abnormal oligomerization and a reduction in the levels of iron-sulfur (Fe-S) cluster proteins
& Labrador, C
Based on the available evidence (Table 1), we conclude that further research should be focused on this issue, especially given the prevalence of NAFLD associated with hypothyroidism
