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No hepatic, splenic, hemopoietic, or duodenal toxicity was noted in this study (168, 169)
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It also modulates systemic mineral balance by suppressing parathyroid hormone (PTH) and fine-tuning the FGF23Klotho signaling axis (41, 42), thus preserving calciumphosphate homeostasis and bonekidney axis integrity
Methamphetamine exposure bidirectionally regulates glutamate receptor expression depending on exposure duration [72, 73], nicotine enhances AMPA and NMDA receptor expression on VTA dopamine neurons [19, 74], and alcohol disrupts glutamate clearance by downregulating GLT-1/xCT and glutamine synthetase [75, 76]
