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Salaiza-Suazo et al, 2024))

Using both an MCAO/R rat models and an in vitro OGD/R cell models (136,137), researchers found that TSA inhibited the expression of pro-inflammatory cytokines (IL-1, IL-6 and TNF-), reduced levels of pro-apoptotic proteins (Bax and Cleaved-Caspase-3) and enhanced the expression of the anti-apoptotic protein Bcl-2

PubMed Cheshire W, Fealey R

doi: 10.1007/s12602-012-9101-3
