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In conclusion, riboflavin is a potential neuroprotective agent affecting a wide range of neurological disorders exemplified by PD, a disorder of neurodegeneration, and migraine headache, a disorder of pain
Primer sequences are listed in Supplementary Table 1

Under oxidative stress conditions, ROS or electrophiles interact with or modify KEAP1 cysteine (Cys) residues, resulting in conformational changes in the KEAP1 protein and subsequent disruption of the NRF2 DLG motif-KEAP1CUL3 complex

[DOI] [PubMed] [Google Scholar] 121.Di Ciaula A, Garruti G, Lunardi Bacceto R
