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For example, although HCQ monotherapy in metastatic pancreatic cancer demonstrated limited effectiveness and variable pharmacodynamic responses, emphasizing the difficulties of consistently inhibiting autophagy in clinical contexts, combination therapies present a more optimistic outlook
The use of leverage results in certain risks, including, among others, the likelihood of greater volatility of the net asset value and the market price of common shares
doi: 10.2527/jas.2016.1070 157 JohnsonJ
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