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A Phase IIb trial of mRNA-4157 in combination with pembrolizumab for patients with resected high-risk melanoma showed that this combination therapy prolonged recurrence-free survival compared with pembrolizumab monotherapy and had a manageable safety profile

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(C) MG detoxification occurs mainly through the glyoxalase system that consists of two enzymes glyoxalase A (GloA) and glyoxalase B (GloB)
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