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Transferrin, apolipoprotein A-IV and apolipoprotein E made cabazitaxel nanocrystals target tumor cells in situ , bloodbrain barrier (BBB)/blood-tumor barrier and activated platelets supporting tumor metastasis, respectively

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These polysaccharides bind to specific receptors on cell membranes and convey information to mitochondria through cyclic adenosine monophosphate (cAMP)
