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Most individuals tolerate these medications, but others may have mild to moderate side effects, particularly during the first few weeks
A healthy lifestyle can help prolong its effects
These peptides exhibited a statistically significant differential abundance between IC/BPS and healthy controls
FIGURE 4 Individual-centric spheroids identified subjects with dose-dependent and dose-independent toxicity at clinically relevant drug exposure Intrinsic DILI is generally not a major concern for the pharmaceutical industry because it is dose-dependent, predictable across populations, and its mechanisms are typically well understood
