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Additional information Communicated by Neal Stewart

Vitamin B12 injections are generally safe and well tolerated, with fewer side effects than corticosteroids

Psoriasis is fundamentally an immune dysregulation disorder
These putative direct targets include the mitochondria-localized isoform of glycerol-3-phosphate dehydrogenase (encoded by the GPD2 gene), the mitochondria-localized isoform of serine hydroxymethyltransferase (encoded by the SHMT2 gene), presenilin enhancer, gamma-secretase subunit (commonly identified as PEN2
