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Synthetic neoantigens formed by proteasome-resistant modification of KRAS G12C peptides with covalent inhibitors are loaded onto HLAs as so-called haptenated peptides or p* (peptides still carrying the covalent inhibitor) and presented as p*MHCs on the cancer cell surface as homogeneously modified epitopes

PMID: 7921999

Genes 8:104 Lagan NC, Balfe J (2018) Question 2: Does heavy metal chelation therapy improve the symptoms of autism spectrum disorder

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