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However, many clinical trials have examined whether lowering homocysteine levels through folic acid, vitamin B12, and vitamin B6 supplementation can reduce cardiovascular disease events, typically in people with a history of cardiovascular disease
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Supplementary Data 1 (download XLSX Statistical source data for Supplementary Figs
Lactic acidosis must usually be ruled out before HPII is diagnosed, as it can lead to secondary hyperprolinemia [19]
