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Functional analysis revealed that acetate degradation and neurotransmitter synthesis pathways were upregulated in the responder group, suggesting that gut microbiota influences the antidepressant effects of SSRIs through these metabolic pathways [121]

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Conclusion Exploring ferroptosis in the context of schizophrenia represents a promising frontier in psychiatric research, offering new perspectives on the cellular and molecular mechanisms underlying this complex disorder

The anterior insula plays a role in subjective experiences that are the read-out of automatic bodily states of emotional reaction 23 , whereas the dorsal ACC (dACC) is involved in appraisal and expression of emotion 24