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However, higher maximal respiration (maximal oxygen consumption rate under high energy demand) and spare capacity (the difference between maximal and basal respiration) were observed in stretched ONH astrocytes compared to unstretched control cells, indicating an increased metabolic flexibility in glial cells during elevated intraocular pressure

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Plasticity of perisynaptic astroglia during ischemia-induced spreading depolarization

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This argument was supported by the combination of BCAT 1 inhibitor and -KG induced tumor cell death in patient-derived IDH WT GBM

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USEPA 1993)

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