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The peptide's four-residue structure makes it one of the smallest bioactive peptides studied in longevity research, and its compact size contributes to favorable pharmacokinetic properties including rapid absorption from subcutaneous injection sites

doi: 10.1007/s12325-020-01542-4

In this regard, numerous investigators have comprehensively evaluated ALAs protective and therapeutic values in sepsis-induced AKI modeled by injection of lipopolysaccharides, though cacal puncture and ligation (CPL)-induced septic AKI have been occasionally used [22,70]

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