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Meanwhile, analysis of the intracellular localization revealed that nuclear-localized MKRN1 was increased in the presence of cisplatin, suggesting that MKRN1 translocates to the nucleus upon DNA damage, and degrades MDM2 in the nucleus (Extended Data Fig
All these approaches are reported to have a less-negative impact on EF, with many of the studies reporting a complete recovery at one-year follow-up [318]
Front Immunol (2012) 3:122
The amount of generated p-nitrophenol was determined from the molar absorption coefficient at pH 8.5, which was 18.290 M 1 cm 1 at pH 10.5
