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In the ileum, the Cbl-IF complex interacts with specific receptors on the mucosal cells, facilitating its uptake through receptor-mediated endocytosis

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The nuclear factor erythroid 2-related factor 2 (Nrf2) pathway is a key transcription factor that regulates the expression of antioxidant-responsive genes, playing a crucial role in this process (168)

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Among all internal organs, the lung is most consistently exposed to exogenous oxidant threats

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