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BSO-washout animals exhibited a small, but significant, decrease in the percentage of correct nosepokes over all nosepokes (both in the active and the inactive port) (Figure 4k) despite the lack of significant differences in correct nosepokes performed after the washout (Figure 4j)

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Studies have demonstrated that PHGDH overexpression enables breast cancer cells to redirect more glutamine into the tricarboxylic acid cycle via the SSP, thereby supporting rapid cell proliferation (68, 69)

173 In healthy volunteers, the total cysteine availability in plasma is 200300 M, distributed across three poolsfree reduced, free oxidised and protein bound