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Genes were clustered hierarchically based on the average topological overlap measure, and modules of coexpressed genes were identified using the cutreeDynamic function with the parameters minClusterSize set to 30, deepSplit set to three and pamStage set to false

In cultured hippocampal neurons, Dihexa treatment for 5 days induced a near 3-fold increase in the number of actin-enriched spines by 41 spines/50m for Dihexa vs