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In summary, oxidative stress plays a critical role in the pathogenesis of OA, and Dp demonstrates significant protective effects against oxidative stress through multiple mechanisms, including inhibiting ROS elevation, activating the Nrf2 and NF-B signaling pathways, inducing autophagy, and regulating apoptosis-related proteins

Snchez-Lpez E, Gomes D, Esteruelas G et al (2020) Metal-based nanoparticles as antimicrobial agents: an overview

While selected drugs briefly solve the challenge, the terrible side effects arent worth it, and so they never provide more than a non permanent solution

Dermatoendocrinol 3 , 121124 (2011)