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Pembrolizumab plus chemotherapy in advanced endometrial cancer
In poplar GSTFs, nearby hydroxylated residues present in the active site signature (often STxT) could be involved in GSH activation (Pgeot et al., 2017)
The increase in metabolism leads to an elevation in the ATP/ADP ratio
Yang WS, Kim KJ, Gaschler MM, Patel M, Shchepinov MS, Stockwell BR (2016) Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
