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Overexpression of disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) in lung cancer reduced LDLR protein stability by promoting its proprotein convertase subtilisin/kexin type 9 (PCSK9)-mediated degradation, leading to decreased cholesterol uptake and triggering cholesterol biosynthesis
10.1111/aab.12232 10 AnthonyK
