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LncRNAs, cirRNAs and miRNAs have been reported to modulate the expression of SLC31A1, ATP7A/7B, FDX1 and other cuproptosis-related genes, but the studies involved are mainly subject to reverse drug resistance before the discovery of cuproptosis and rarely referred to Cu-dependent cell death so far (Yu et al., 2020)

2021;375:n2643

doi: 10.1038/s41577-020-00490-y 56 LVBWangYMaDChengWLiuJYongTet al

MSCs cultured under relatively high cell density that increases cellular GSH levels enhances hyaline cartilage regeneration To confirm that the in vivo regenerative capacity of MSCs could vary with the cell culture conditions, we cultured hES-MSCs under two different culture conditions (5 10 3 cells/cm 2
