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[DOI] [PMC free article] [PubMed] [Google Scholar] 16.Granneman JG, Moore HP, Krishnamoorthy R, Rathod M

10002000 g daily) can correct deficiency in some cases (even without intrinsic factor, because a small fraction can be absorbed passively)

Unexpectedly elevated B12 levels without supplementation may indicate liver disease, renal impairment, or myeloproliferative disorders requiring investigation

Start at lower doses to assess tolerance and adjust based on results
