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Significant gut flora modification was observed in the opioid cohort, especially in encephalopathic patients on opioids with lower abundance of the autochthonous families compared to others (Clostridiales XIV and Lachnospiraceae ) along with a decrease in Bacteroidaceae relative abundance
Wang, Taurine protects dopaminergic neurons in a mouse Parkinsons disease model through inhibition of microglial M1 polarization, Cell Death & Disease 9(4) (2018) 435
A significant heterogeneity was also evident
