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For example, a frequently used substrate to study TGM2, carbobenzoxy-L-glytaminylglycine, has a K m of 22 mM (Folk and Cole, 1965)

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Other clinically relevant species, such as Escherichia coli , Salmonella enterica , Neisseria gonorrhoeae , and Mycobacterium tuberculosis , also pose serious therapeutic challenges and contribute significantly to the global AMR burden [6, 7]

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