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doi: 10.3390/genes12071006 179 ChengRDhorajiaVVKimJKimY

Weiss DJ, Armstrong PJ, Gagne J
Consistent with inhibition of GSTP1, a key cellular detoxification enzyme, Molidustat treatment led to a significant increase in intracellular reactive oxygen species (ROS) levels

Co-culturing ferroptotic cancer cells with dendritic cells (DCs) reveals that ferroptotic cells decrease maturation of DCs and dampen antigen cross-presentation, and hence inhibit adaptive immune response and promote tumor growth [232]