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Elevated MG promotes the formation of advanced glycation adducts with DNA and proteins, resulting in genome instability and triggering cell death [122]

Recently MGF has been shown to have neuroprotective effects in an ischemic brain model [15] and it had been reported to be markedly more effective than IGF-I [16]

Strachan, M

[DOI] [PubMed] [Google Scholar] Huang M, Cai G, Baugh LM, Liu Z, Smith A, Watson M, Popovich D, Zhang T, Stawski LS, Trojanowska M, Georgakoudi I, Black LD, Pioli PA, Whitfield ML, Garlick J (2020) systemic sclerosis dermal fibroblasts induce cutaneous fibrosis through lysyl oxidase-like 4: new evidence from three-dimensional skin-like tissues