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Alves E, Binienda Z, Carvalho F, Alves CJ, Fernandes E, de Lourdes BM, Tavares MA, Summavielle T (2009) Acetyl-L-carnitine provides effective in vivo neuroprotection over 3, 4-methylenedioximethamphetamine-induced mitochondrial neurotoxicity in the adolescent rat brain

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However, autophagosome markers are decreased which may indicate there was a defect in the removal of mitochondria fragments, while reduced mitophagy markers may indicate that there were less healthy mitochondria fragments to be recycled

Magel2-null mice are hyper-responsive to setmelanotide, a melanocortin 4 receptor agonist