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doi: 10.3389/fphar.2022.938447 Received 07 May 2022 Accepted 23 May 2022 Published 14 June 2022 Volume 13 - 2022 Edited by Dongwei Zhang, Beijing University of Chinese Medicine, China Reviewed by Yan Zhang, Shanghai University of Traditional Chinese Medicine, China Lili Wang, Beijing University of Chinese Medicine, China Yang Guo, Nanjing University of Chinese Medicine, China Updates Copyright 2022 Lu, Hu, Ma and Shuai

While our bodies naturally produce glutathione, several factors, including poor diet, chronic disease, infections, and constant stress, can deplete its levels

After treatment cycles, maintenance with alternative ingredients is necessary to preserve results

Therefore, it is critical to maintain cellular iron homeostasis, and intracellular iron storage/release and import/export are intricately regulated (Figure 2)