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doi: 10.1046/j.1523-1755.2000.00261.x
Deficits in acetylcholine and abnormal phospholipid metabolism have been reported in postmortem studies of the brains of AD patients (12)
Moderate mitral regurgitation and a small pericardial effusion were also detected
In addition, betaine can also be synthesized de novo from dietary choline in the mammalian liver and kidney via a two-step enzymatic process in which choline is first oxidized to betaine aldehyde by choline dehydrogenase
