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D., Ley, S

Dysfunction of CCS may lead to SOD1 aggregation, causing neuronal oxidative damage

Therefore, LPS can be used in combination with D-GalN to induce ALF in animal models (25,26) and TNF- combined with D-GalN can be used to create an L02 cell injury model (27)

Cross-talk of GSH with zinc and Fe homeostasis was also reported (Shanmugam et al., 2012)