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To study their role in ferroptosis in ER+ breast cancer models, we depleted AGPAT3 and FAR1 using siRNA SMARTpools or a CRISPR sgRNA approach and treated MCF-7 and T47D cells with palbocicilib, RSL3, or the combination in clonogenic assays (Fig

AC effectively mitigated stress-induced gastric damage while also exhibiting notable antidepressant effects, highlighting its potential as a dual-function therapeutic agent

& Shlomi, T