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Depression and Low Mood: SAMe acts as a direct precursor for the synthesis of serotonin, dopamine, and norepinephrine, effectively addressing the biochemical imbalances that drive depression and anhedonia in chronic illness

The result is an enhancement of the downstream mechanisms of the itch receptor, i.e

Borrelli R, Di Donato M, Peluso A

One of the side effects of anemia is an inability to convert fats and proteins into energy
