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Metronidazole targets stress responses in Helicobacter pylori, and ether analogues showed enhanced antibacterial potency and favourable pharmacology and achieved bacterial eradication in a mouse model.

To test if even higher intracellular glutathione levels could be achieved and if this might lead to increased tolerance, we overexpressed the genes from two bacterial genera and assessed the recombinants in simultaneous saccharification and fermentation (SSF) with steam pretreated spruce hydrolysate containing 10% solids

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