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doi: 10.3389/fnsys.2014.00038 Received 24 November 2013 Accepted 03 March 2014 Published 13 May 2014 Volume 8 - 2014 Edited by Mikhail Lebedev, Duke University, USA Reviewed by Kimberly Simpson, University of Mississippi Medical Center, USA

SR 141716, better known as Rimonabant, is an inverse agonist at the type-1 cannabinoid receptor (CBR1), and thus belongs to the first pharmacological category of nootropics

Most users notice initial effects within 7-14 days, with pain reduction being the earliest indicator
